Career Summary: Dr. Ngo is Assistant Professor, Division of hematopoietic stem cell and leukemia Research, Beckman Research Institute of City of Hope (Duarte, CA). He received his Ph.D. in Biomedical Sciences in 2001 from the University of California San Francisco. From 2001–06, he undertook a postdoctoral fellowship at the National Cancer Institute, National Institutes of Health (NIH, Bethesda, MD), followed by a research fellowship there (2006–07), and a promotion to Staff Scientist (2007–10). In addition to his award from STOP CANCER, he is the recipient of the Damon Runyon Cancer Research Postdoctoral Fellowship (2001–04) and the NIH Cancer Research Training Award (2004–06).

Year STOP CANCER Award was received: 2012 Rosalind and Arthur Gilbert Foundation Seed Grant; 2013 RCDA

Description of research performed: leukemias and lymphomas can occur when there is disruption of the normal development and activation of B cells. The research in Dr. Ngo’s laboratory aims to discover abnormal signal transduction pathways and elucidate the molecular pathogenesis of germinal center-derived B cell tumors as well as other hematologic malignancies.

Results of research: Better understanding the molecular basis of aberrant signal transduction pathways critical for cancer growth will allow Dr. Ngo’s team to identify effective molecular targets and devise better therapeutic strategies for cancer treatments.