Ling Li, Ph.D.
Research performed at: City of Hope Comprehensive Cancer Center
Specialty/Research Area: Acute Myeloid Leukemia, Leukemia Stem Cells
Career Summary: Dr. Li is an Assistant Professor of Division of hematopoietic stem cell and leukemia Research within the hematologic Malignancies and stem cell Transplantation Institute at City of Hope (Duarte, CA). He received his Ph.D. from the Cancer Institute of Zhejiang University School of Medicine, China. He did his postdoctoral fellowship at City of Hope from 2008–2012. In 2013, he was promoted to the position of Research Scientist. He joined COH as an Assistant Professor in 2015. In addition to his STOP CANCER Award, Dr. Li is the recipient of an NIH K99/R00 Pathway to Independence Award (2014). This year, Dr. Li was also awarded a grant from The Margaret E. Early Medical Research Trust.
Year STOP CANCER Award was received: 2017 Research Career Development Award
Description of research performed: Dr. Li is very active in the area of leukemia research. His research focuses on studying the molecular mechanisms that initiate or maintain the leukemia, specifically acute myeloid leukemia (AML).
Results of research: Dr. Li has made great contributions to the field of leukemia stem cell (LSC) research by bringing a greater understanding of the mechanisms of resistance of these cells to the current therapies. Dr. Li’s laboratory is currently studying epigenetic-related resistance mechanisms of LSC to tyrosine kinase inhibitors (TKI) treatment. The primary goal of this effort is to develop novel therapeutics to specifically target LSC and advance these strategies to clinical trials in AML.